|LETTER TO EDITOR
|Year : 2020 | Volume
| Issue : 1 | Page : 63-64
Thrombotic thrombocytopenic purpura during pregnancy
Antonio Ponzetto1, Natale Figura2
1 Departmen of Medical Sciences, University of Torino, Corso AM Dogliotti 14, Torino, Italy
2 Department of Biotechnology Chemistry and Pharmacy University of Siena, Via A. Moro, Siena, Italy
|Date of Submission||20-Sep-2019|
|Date of Acceptance||25-Oct-2019|
|Date of Web Publication||11-Mar-2020|
Dr. Antonio Ponzetto
Department of Medical Sciences, University of Torino, Corso AM Dogliotti 14, Torino -10126
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Ponzetto A, Figura N. Thrombotic thrombocytopenic purpura during pregnancy. J Obstet Anaesth Crit Care 2020;10:63-4
We found of interest the clinical case of thrombotic thrombocytopenic purpura (TTP) during pregnancy presented by Basta. He reports of a 39-year-old lady who had had previous episodes of TTP correlated with pregnancy; therefore, a presumptive diagnosis of acquired TTP was made. We would like to stress the correlation between TTP and infection by Helicobacter pylori, in particular when it belongs to the so-called pathogenic strain, which is characterized by the synthesis of the cytotoxin-associated gene A protein (CagA). The cure of this bacterium was followed by regression of TTP. In the case reported by Basta, the lady's previous pregnancy was complicated by pre-eclampsia (PE), another ailment strongly associated with infection by Helicobacter pylori: we observed that in Turin, Italy, 90.6% of preeclamptic women giving birth to small-for-gestational age newborns were infected by CagA positive strains of the bacterium, compared to 22.4% of uneventful pregnancies (odds ratio, 17.66). Several other reports confirmed our findings. We believe that the prudent physician should search for the infection by pathogenic strains of H. pylori prior to every pregnancy.
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Conflicts of interest
There are no conflicts of interest.
| References|| |
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