Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Journal of Obstrectic Anaesthesia and Critical Care
Search articles
Home Print this page Email this page Small font size Default font size Increase font size Users Online: 955
ORIGINAL ARTICLE
Year : 2013  |  Volume : 3  |  Issue : 2  |  Page : 84-90

A randomized double-blind comparison of low-dose and high-dose bupivacaine for caesarean section in severely preeclamptic women using invasive blood pressure monitoring


1 Department of Anaesthesia and Intensive Care, Post Graduate Institute of Medical Education and Research, Chandigarh, India
2 Department of Obstetrics and Gynecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Kajal Jain
Department of Anaesthesia, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh - 160 012
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2249-4472.123302

Rights and Permissions

Background: The effect of a low dose of spinal local anesthetic on the incidence of hypotension has not been evaluated till date in severely preeclamptic women undergoing cesarean delivery. In this study, we compared the mean arterial pressure changes associated with low and conventional doses of spinal anesthetic in these women using invasive pressure monitoring. Materials and Methods: Twenty four severely preeclamptic women scheduled for elective cesarean delivery were randomly allocated to receive 7.5 mg [Group 1] or 10 mg [Group 2] of bupivacaine with 20 μg of fentanyl for spinal anesthesia. Heart rate and mean arterial pressure (MAP) were measured continuously using invasive arterial pressure monitoring. Phenylephrine boluses were used to maintain the MAP of >80% of baseline. The incidence of hypotension was compared between the two groups. Neonatal outcome was assessed using Apgar scores, umbilical cord blood gases, and need for resuscitation. Results: Incidence of hypotension was less in Group 1 as compared to Group 2 (41.6% vs. 91.6%, P = 0.009). Duration of hypotension was significantly longer in Group 2 compared to Group 1 (P = 0.005). Hypotensive episodes requiring vasopressors were more frequent in Group 2 (1.5 [1-3] vs. 0 [0-1]), P = 0.01) [Table 2]. There was no difference in Apgar scores, umbilical cord blood gases, and need for resuscitation between the two groups. Conclusion: Low dose of spinal bupivacaine resulted in a lower incidence of hypotension, higher predelivery MAP and decreased use of vasopressors in severely pre-eclamptic women undergoing cesarean section.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3050    
    Printed57    
    Emailed1    
    PDF Downloaded593    
    Comments [Add]    
    Cited by others 1    

Recommend this journal